When we get injured, bleeding stops after a while, the wound is closed, and eventually, it becomes a scab and heals. "Platelets" contained in the blood play a role in this series of processes. And focusing on the function of platelets, PRP (Platelet-Rich Plasma) therapy has been adopted in the fields of cosmetic surgery and sports medicine as well as an infertility treatment for several years. It is a regenerative medicine that promotes the healing of various parts by treating the repairability of growth factors contained in platelets in one's own blood and enhancing the "healing power" inherent in humans.
Then, what kind of effect is expected of PRP in infertility treatment? One is an increase in the number of eggs. As I introduced before in this column, all female eggs are produced during the fetal period, and their numbers peak before birth and continue to decline little by little. Therefore, with aging, the number and quality of eggs decrease, leading to infertility. No matter how much the medicine induces ovulation, there is an individual limit to the ovarian reserve, and if the FSH (follicle-stimulating hormone) level are very high or AMH (anti-Müllerian hormone) level are low, it was the fact that "when there is no egg left, nothing comes out".
However, by injecting PRP into the ovary, it is possible to rejuvenate the ovarian function, promote the development of follicles that wrap the egg, and produce more mature eggs. Moreover, increasing the number of eggs improves the number of eggs collected by in vitro fertilization (IVF), the success rate, and the pregnancy rate. It is a glimmer of hope for those who have high FSH and low AMH but have no way to address it, or who have trouble with IVF due to the problem of the number of the egg.
PRP is also effective for people under the age of 40 who have early menopause. PRP brings the ovarian function restored and develops the follicle to produce the egg again. It would be possible to become pregnant with their own egg by IVF.
Another effective treatment is for the thin endometrial. Some people may be aware that "I had miscarriage repeatedly many times" and "My implantation does not continue even though good quality fertilized eggs have been transferred several times". In those cases of these repeated implantation failures, it is suspected to be caused by the thinness of the endometrium. The endometrium plays an important role like a bed on which a fertilized egg is implanted and a certain thickness is needed to continue implantation.
If you have thin endometrial, by injecting PRP into the uterus, several growth factors in platelets proliferate cells in the endometrium, improve angiogenesis. And you can be greatly expected that it will improve the implantation rate of fertilized eggs and continue pregnancy.
The treatment method is very simple. The blood collected from your arm is placed in a dedicated centrifuge and only PRP is extracted. Then, just inject it into the ovaries or uterus. Since the treatment uses your blood, it is very safe and there is no concern about allergic reactions. After the injection, make sure that the egg is made or that the endometrium is thick enough, and then proceed to the next step. The effect of PRP lasts for about 2 months, and if you try to do IVF, you should do it within that period.
When we get injured, bleeding stops after a while, the wound is closed, and eventually, it becomes a scab and heals. “Platelets” contained in the blood play a role in this series of processes. And focusing on the function of platelets, PRP (Platelet-Rich Plasma) therapy has been adopted in the fields of cosmetic surgery and sports medicine as well as an infertility treatment for several years. It is a regenerative medicine that promotes the healing of various parts by treating the repairability of growth factors contained in platelets in one’s own blood and enhancing the “healing power” inherent in humans.